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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026661Generated: November 3, 2026

Triethylamine → HCID 11374585, compound

https://huagongshe.com/reaction/1026661

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantMethanesulfonyl chlorideHCID 31297—
ReactantHCID 11394934HCID 11394934—
SolventDichloromethaneHCID 6344—
ProductHCID 11374585HCID 1137458575%

Reaction Steps

The title compound was prepared by reacting (S)—N-{3-[4-(4-fluoro-4-aminomethyl piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.30 mmol) with methane sulfonyl chloride (1.40 mmol) and triethylamine (2.08 mmol) in dichloromethane (10 ml) at a temperature 25° C. for 2 hours followed by purification of the compound using silica gel column chromatography in 75% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729269B2
Source datasetuspto-grants-2014_05
ORD IDord-2e7768da33b444a4b1bcb30f1ea88395
Source noteuspto-grants-2014_05