HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium ethoxide → HCID 11429747, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | HCID 11382912 | HCID 11382912 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 11429747 | HCID 11429747 | 55% |
Reaction Steps
The title compound was prepared by reacting (S)—N-{3-[4-(1-oxa-6-aza-spiro[2.5]oct-6-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.0 mmol) with sodium ethoxide (1.6 mmol) in ethanol (10 ml) at a temperature 60° C. for 6 hours and by purifying the compound by silica gel column chromatography in 55% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729269B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-7528523b9fc04656a223a45a26843888 |
| Source note | uspto-grants-2014_05 |