HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Cyanide → HCID 11156399, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | 2,3,4-Trifluoroaniline | HCID 77468 | — |
| Reactant | N-[(5S)-3-[3-fluoro-4-(4-oxopiperidinyl)phenyl]-2-oxo-5-oxazolidinyl]methylacetamide | HCID 54375226 | — |
| Product | HCID 11156399 | HCID 11156399 | 68% |
Reaction Steps
By using procedure as described in Example 45 and by reacting (S)—N-{3-[4-(4-oxo-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide with sodium cyanide and 2,3,4-trifluoroaniline the compound was obtained in 68% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729269B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-fc95e209a56f4768aed8d9da2705b6ee |
| Source note | uspto-grants-2014_05 |