HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 60998602, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Iodoxybenzoic acid | HCID 108794 | — |
| Reactant | HCID 69184067 | HCID 69184067 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 60998602 | HCID 60998602 | 99.9% |
Reaction Steps
A solution of 2-iodoxybenzoic acid (441 mg) in dimethylsulfoxide (5 mL) was added to a solution of {2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}methanol (361 mg) in dimethylsulfoxide (10 mL) and the resulting mixture was stirred at room temperature overnight. After water was added, the mixture was filtered through Celite and then extracted with ethyl acetate. The solvent was distilled off under reduced pressure to afford the title compound (358 mg) as the residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729271B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-51d3b8a9a8804c08864017e8953ce2a4 |
| Source note | uspto-grants-2014_05 |