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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026754Generated: October 31, 2026

Water → HCID 60998602, compound

https://huagongshe.com/reaction/1026754

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant2-Iodoxybenzoic acidHCID 108794—
ReactantHCID 69184067HCID 69184067—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 60998602HCID 6099860299.9%

Reaction Steps

A solution of 2-iodoxybenzoic acid (441 mg) in dimethylsulfoxide (5 mL) was added to a solution of {2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}methanol (361 mg) in dimethylsulfoxide (10 mL) and the resulting mixture was stirred at room temperature overnight. After water was added, the mixture was filtered through Celite and then extracted with ethyl acetate. The solvent was distilled off under reduced pressure to afford the title compound (358 mg) as the residue.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729271B2
Source datasetuspto-grants-2014_05
ORD IDord-51d3b8a9a8804c08864017e8953ce2a4
Source noteuspto-grants-2014_05