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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026761Generated: November 3, 2026

Hydrogen chloride-ethyl acetate → HCID 86690485, compound

https://huagongshe.com/reaction/1026761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen chloride-ethyl acetateHCID 21866389—
ReactantHCID 86690487HCID 86690487—
SolventEthyl AcetateHCID 8857—
ProductHCID 86690485HCID 86690485—

Reaction Steps

To a solution of tert-butyl N-cyclobutyl-N-[(1-methyl-1H-imidazol-4-yl)carbonyl]glycinate (200 mg) in ethyl acetate (4 mL) was added 4N hydrochloric acid/ethyl acetate solution (4 mL), and the mixture was stirred at room temperature overnight. The solvent was distilled off under reduced pressure to afford N-cyclobutyl-N-[(1-methyl-1H-imidazol-4-yl)carbonyl]glycine hydrochloride (150 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729271B2
Source datasetuspto-grants-2014_05
ORD IDord-48d11973b5b64a799e99732e193b8aa6
Source noteuspto-grants-2014_05