HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen chloride-ethyl acetate → HCID 86690485, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | HCID 86690487 | HCID 86690487 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86690485 | HCID 86690485 | — |
Reaction Steps
To a solution of tert-butyl N-cyclobutyl-N-[(1-methyl-1H-imidazol-4-yl)carbonyl]glycinate (200 mg) in ethyl acetate (4 mL) was added 4N hydrochloric acid/ethyl acetate solution (4 mL), and the mixture was stirred at room temperature overnight. The solvent was distilled off under reduced pressure to afford N-cyclobutyl-N-[(1-methyl-1H-imidazol-4-yl)carbonyl]glycine hydrochloride (150 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729271B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-48d11973b5b64a799e99732e193b8aa6 |
| Source note | uspto-grants-2014_05 |