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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026768Generated: November 1, 2026

Acetic Acid → HCID 86690496, compound

https://huagongshe.com/reaction/1026768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHCID 86690497HCID 86690497—
SolventDimethylformamideHCID 6228—
ProductHCID 86690496HCID 866904969.7%

Reaction Conditions

Temperature120 °C

Reaction Steps

A mixture of N-{2-[({amino[4-(trifluoromethoxy)phenyl]methylidene}amino)oxy]-2-oxoethyl}-N-cyclobutyl-1-methyl-1H-imidazole-4-carboxamide (75 mg), acetic acid (0.5 mL) and dimethylformamide (0.5 mL) was stirred while heating at 120° C. for 2 hr. After the solvent was distilled off under reduced pressure, the resulting residue was purified by HPLC to afford the title compound (7 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729271B2
Source datasetuspto-grants-2014_05
ORD IDord-ad271569084d4586859898bd485bd27e
Source noteuspto-grants-2014_05