Methyl iodide → HCID 67134619, compound

HRID 1026776Notes

Reaction equation

[CH2:1]([N:5]1[C:9](=[O:10])[N:8]([CH2:11][CH2:12][CH2:13][CH3:14])[C:7](=[O:15])[P:6]1[CH3:16])[CH2:2][CH2:3][CH3:4].[CH3:17][I:18]>>[I-:18].[CH2:1]([N:5]1[C:9](=[O:10])[N:8]([CH2:11][CH2:12][CH2:13][CH3:14])[C:7](=[O:15])[P+:6]1([CH3:17])[CH3:16])[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 67134546HCID 67134546, compound

Product 1

HCID 67134619HCID 67134619, compound

Conditions

Temperature: 80 °C

Procedure

A mixture of 820 mg (3.3 mmol) of 1,4-dibutyl-2-methyl-1,4,2-diazaphospholidine-3,5-dione (cf. Ex. 3) with 6.27 g (44 mmol) of methyl iodide (from Aldrich) was heated at reflux (bath temperature: to 80° C.) while stirring with a magnetic stirrer bar for 24 h. The yellow mixture, whose viscosity had risen noticeably, was analysed by NMR spectroscopy without further workup:

Workup

temperaturewas heated

Sources & evidence

ORD record: ord-f27c2a14ad6a458ca55f3a0e595e284d
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08729304B2

Reaction notes

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