4-(2-Thienyl)piperidine hydrochloride → 3-Bromo-7-benzylamino-6-[4-(thiophen-2-yl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine

Participants

Reaction Steps

In the same manner as in Example 21, step 5 and using 7-benzylamino-3-bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.10 g, 0.29 mmol) obtained in Example 22, step 3 and 4-(thiophen-2-yl)piperidine hydrochloride (0.07 g, 0.35 mmol), the title compound (0.14 g, 99%) was obtained.

Provenance & Evidence