HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylisoxazole-4-sulfonamide → N-[7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-3,5-dimethylisoxazole-4-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylisoxazole-4-sulfonamide | HCID 4962303 | — |
| Reactant | 7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 67540621 | — |
| Product | N-[7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-3,5-dimethylisoxazole-4-sulfonamide | HCID 67540876 | 66% |
Reaction Steps
In the same manner as in Example 1, step 6 and using 7-(2-methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.08 g, 0.18 mmol) obtained in Example 39, step 2 and 3,5-dimethylisoxazole-4-sulfonamide (0.16 g, 0.88 mmol), the title compound (0.07 g, 66%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-6f56266cf75b449584d64c537808a84a |
| Source note | uspto-grants-2014_05 |