HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidine → 7-(2-Chloro-5-methylphenylamino)-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 7-(2-Chloro-5-methylphenylamino)-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid | HCID 67540770 | — |
| Product | 7-(2-Chloro-5-methylphenylamino)-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 67540390 | 84% |
Reaction Steps
In the same manner as in Example 21, step 5 and using 7-(2-chloro-5-methylphenylamino)-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (72 mg, 0.17 mmol) obtained in step 2 and 4-phenylpiperidine (37 mg, 0.26 mmol), the title compound (72 mg, 84%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-8636c7ff441a4a7fac43590235d80a63 |
| Source note | uspto-grants-2014_05 |