Piperidine, 4-(2-naphthalenyl)-, hydrochloride (1:1) → 3-Ethoxycarbonyl-7-(2-fluoro-5-methylphenylamino)-6-[4-(2-naphthyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine

Participants

Reaction Steps

In the same manner as in Example 21, step 5 and using 3-ethoxycarbonyl-7-(2-fluoro-5-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (120 mg, 0.33 mmol) obtained in Example 90, step 2 and 4-(2-naphthyl)piperidine hydrochloride (WO1997/037979, 100 mg, 0.40 mmol), the title compound (89 mg, 49%) was obtained.

Provenance & Evidence