HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-methylaniline → Ethyl 3-bromo-7-(4-fluoro-2-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-methylaniline | HCID 67982 | — |
| Reactant | Ethyl 3-bromo-7-chloropyrazolo[1,5-a]pyrimidine-6-carboxylate | HCID 57345881 | — |
| Product | Ethyl 3-bromo-7-(4-fluoro-2-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate | HCID 67540887 | 99.9% |
Reaction Steps
In the same manner as in Example 1, step 4 and using ethyl 3-bromo-7-chloropyrazolo[1,5-a]pyrimidine-6-carboxylate (3.5 g, 11.4 mmol) obtained in Example 22, step 1 and 4-fluoro-2-methylaniline (1.53 mL, 22.8 mmol), the title compound (4.48 g, 99%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-20186268401b48af8e3237d0911b42cf |
| Source note | uspto-grants-2014_05 |