7-(2,5-Dimethylphenylamino)-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid → 7-(2,5-Dimethylphenylamino)-3-ethoxycarbonyl-6-(2-methylspiro[inden-1,4'-piperidine]-1'-ylcarbonyl)pyrazolo[1,5-a]pyrimidine

Participants

Reaction Steps

In the same manner as in Example 21, step 5 and using 7-(2,5-dimethylphenylamino)-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.100 g, 0.282 mmol) obtained in Example 88, step 2 and 2-methylspiro[inden-1,4′-piperidine] (0.062 g, 0.313 mmol), the title compound (0.098 g, 65%) was obtained.

Provenance & Evidence