HuagongsheHuagongshe Chemistry Print Report · For research reference only
3H-spiro[isobenzofuran-1,4'-piperidin]-3-one hydrochloride → HCID 178469966, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3H-spiro[isobenzofuran-1,4'-piperidin]-3-one hydrochloride | HCID 22380631 | — |
| Reactant | HCID 178469973 | HCID 178469973 | — |
| Product | HCID 178469966 | HCID 178469966 | 89% |
Reaction Steps
In the same manner as in Example 1, step 2 and using 3-ethoxycarbonyl-7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.436 g, 1.74 mmol) obtained in Example 19, step 2 and 3-oxo-3H-spiro[isobenzofuran-1,4′-piperidine]hydrochloride (Journal of Organic Chemistry, 1976, vol. 15, item 2628, 0.500 g, 2.09 mmol), the title compound (0.680 g, 89%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-5adfb3d9d33d426faabc17d690bee690 |
| Source note | uspto-grants-2014_05 |