HuagongsheHuagongshe Chemistry Print Report · For research reference only
3H-spiro(2-benzofuran-1,4'-piperidine) hydrochloride → HCID 67540856, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3H-spiro(2-benzofuran-1,4'-piperidine) hydrochloride | HCID 22509330 | — |
| Reactant | 3-Bromo-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidine-6-carboxylic acid | HCID 67540363 | — |
| Product | HCID 67540856 | HCID 67540856 | 94% |
Reaction Steps
In the same manner as in Example 21, step 5 and using 7-benzylamino-3-bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.754 g, 2.18 mmol) obtained in Example 22, step 3 and 3H-spiro[isobenzofuran-1,4′-piperidine]hydrochloride (Journal of Organic Chemistry, 1976, vol. 15, item 2628, 0.491 g, 0.218 mmol), the title compound (0.484 g, 94%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-6acacbf54b344122a453d06a5176ed47 |
| Source note | uspto-grants-2014_05 |