HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrazole-4-boronic acid → HCID 86710666, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrazole-4-boronic acid | HCID 17750278 | — |
| Reactant | 1-Bromo-5-chloro-4-iodo-2-methoxybenzene | HCID 50997848 | — |
| Product | HCID 86710666 | HCID 86710666 | 72.5% |
Reaction Steps
Following standard GENERAL METHOD 1-4 for Suzuki coupling using (1H-pyrazol-4-yl)boronic acid (161 mg, 1.44 mmol) and 1-bromo-5-chloro-4-iodo-2-methoxybenzene (500 mg, 1.44 mmol) afforded 4-(4-bromo-2-chloro-5-methoxyphenyl)-1H-pyrazole (300 mg) MS [M+H+]=286.8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729263B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-77e324daa6d5450c8e583a21d46f6947 |
| Source note | uspto-grants-2014_05 |