Hydrochloric Acid → 4-(2-Fluoro-phenyl)-1-(4-hydroxy-butyl)-1H-pyrimidin-2-one

HRID 102730Notes

Reaction equation

HRID 102730 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH2:8][CH2:9][CH2:10][n:11]1[c:12](=[O:24])[n:13][c:14](-[c:17]2[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1)([CH3:5])([CH3:25])[CH3:26].[ClH:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1>>[OH:6][CH2:7][CH2:8][CH2:9][CH2:10][n:11]1[c:12](=[O:24])[n:13][c:14](-[c:17]2[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 592427901-[4-(tert-Butyl-dimethyl-silanyloxy)-butyl]-4-(2-fluoro-phenyl)-1H-pyrimidin-2-one

Product 1

HCID 592427824-(2-Fluoro-phenyl)-1-(4-hydroxy-butyl)-1H-pyrimidin-2-one

Sources & evidence

ORD record
ord-e0a246ec3218433ba0bf21a58d9f77a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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