HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Difluorobenzene-1-sulfonyl chloride → 3,4-Difluoro-N-{4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenyl}-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Difluorobenzene-1-sulfonyl chloride | HCID 2736913 | — |
| Reactant | 4-[(S)-3-((S)-2-Methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine | HCID 67479147 | — |
| Product | 3,4-Difluoro-N-{4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenyl}-benzenesulfonamide | HCID 67479430 | — |
Reaction Steps
The title compound was synthesized essentially in the same manner as Example 28 by employing 4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine (Intermediate 14) and 3,4-difluorobenzene sulfonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735385B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-0b55fb9f3789401cb485966ea75bbf73 |
| Source note | uspto-grants-2014_05 |