HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 67246433, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 15384455 | HCID 15384455 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67246433 | HCID 67246433 | — |
Reaction Steps
A solution of (2-benzyl-isoxazolidin-5-ylmethyl)-carbamic acid tert-butyl ester (Step A, 0.5 g) in dichloromethane (10 ml) was treated with trifluoroacetic acid (1.95 g). The solution was stirred at room temperature for 4 hours then concentrated in vacuo to afford the crude title product, which was used directly for the next step. LCMS (Method F) 0.20 min, M+H 194.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735362B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-898f86f6e4c34faf8f288b5596f240ef |
| Source note | uspto-grants-2014_05 |