HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-(3,5-Dichlorophenyl)-5-(tri fluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid → HCID 68267481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-(3,5-Dichlorophenyl)-5-(tri fluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid | HCID 23159811 | — |
| Reactant | HCID 68267480 | HCID 68267480 | — |
| Product | HCID 68267481 | HCID 68267481 | 37.5% |
Reaction Steps
The compound obtained in Step C (94 mg) was deprotected and coupled with 4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-2-methyl-benzoic acid (0.125 g) (prepared according to WO 2009/080250) as described in Example 4, Steps B and C to afford the title compound as a brown solid (65 mg). LCMS (Method F) 2.02 min, M−H 654/655.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735362B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-91b6e872a07f473eb985931cc2ee7380 |
| Source note | uspto-grants-2014_05 |