HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1027886Generated: October 30, 2026
Trifluoroacetic acid → 6-Benzyl-2,6-diazaspiro[3.5]nonane 2,2,2-trifluoroacetate
https://huagongshe.com/reaction/1027886
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 6-benzyl-2,6-diazaspiro[3.5]nonane-2-carboxylate | HCID 50878573 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 6-Benzyl-2,6-diazaspiro[3.5]nonane 2,2,2-trifluoroacetate | HCID 69226180 | — |
Reaction Steps
tert-butyl 6-benzyl-2,6-diazaspiro[3.5]nonane-2-carboxylate (0.18 g) was mixed with CH2Cl2 (1 mL) and TFA (1 mL), then heated at 60° C. for 2 minutes and concentrated to dryness to provide the title compound as the trifluoroacetic acid salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08735411B2 |
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| Source dataset | uspto-grants-2014_05 |
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| ORD ID | ord-f6d483192b19417ebf13968c9f6dfb1c |
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| Source note | uspto-grants-2014_05 |
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