Dimethylformamide → 3-Butyl-2,5-dioxoimidazolidine 1-heptylcarboxamide

HRID 1028160Notes

Reaction equation

HRID 1028160 reaction equation
[CH2:1]([N:5]1[CH2:9][C:8](=[O:10])[NH:7][C:6]1=[O:11])[CH2:2][CH2:3][CH3:4].N([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=C=O.C[N:23]([CH:25]=[O:26])C>>[CH2:1]([N:5]1[CH2:9][C:8](=[O:10])[NH:7][C:6]1=[O:11])[CH2:2][CH2:3][CH3:4].[CH2:15]([C:25]([NH2:23])=[O:26])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 1185061-Butylimidazolidine-2,4-dioneHCID 138341n-Heptyl isocyanate

Product 1

HCID 1317314153-Butyl-2,5-dioxoimidazolidine 1-heptylcarboxamide

Procedure

1-Butylimidazolidine-2,4-dione (100 mg, 0.64 mmol) and 1-isocyanatoheptane (108.5 mg, 0.768 mmol) were reacted in DMF in analogy to example 1. Yield: 15 mg (8%), M+H+: 298.18.

Sources & evidence

ORD record
ord-ab997e2a1df548949bbf4cd9713870b6
Source dataset
uspto-grants-2014_05
Patent number
US08735437B2

Reaction notes

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