Sodium Hydroxide → HCID 66935854, compound

HRID 1028224Notes

Reaction equation

HRID 1028224 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([CH:7]1[CH2:12][CH2:11][CH:10]([CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:9][CH2:8]1)[CH3:6])C.[OH-].[Na+]>>[C:17]([O:16][C:14]([CH2:13][CH:10]1[CH2:9][CH2:8][CH:7]([CH:5]([CH3:6])[C:4]([OH:21])=[O:3])[CH2:12][CH2:11]1)=[O:15])([CH3:20])([CH3:18])[CH3:19]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 66935915HCID 66935915, compound

Product 1

HCID 66935854HCID 66935854, compoundYield 78%

Procedure

2-(4-Tert-butoxycarbonylmethyl-cyclohexyl)-propionic acid ethyl ester (2.46 g) obtained in Example (106a) was hydrolyzed with 1 N NaOH in the same way as in (Example 2) to obtain the title compound (1.72 g, 78%) as a colorless oil.

Sources & evidence

ORD record
ord-e8b9b729023d4e03b6ccf20d2cc45d2d
Source dataset
uspto-grants-2014_05
Patent number
US08735425B2

Reaction notes

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