反应详情

2.0 g 5-tert-butyl-2-methoxy-1,3-dinitro-benzene are dissolved in 20 ml of ethanol, combined with 100 μl water and 100 mg of 10% palladium on activated charcoal and then refluxed. 1.9 ml of 4-methyl-cyclohexene are added and the mixture is refluxed for a further 2 hours. Then a further 950 μl of 4-methyl-cyclohexene are added dropwise and then refluxed for 16 hours. The solvents are then eliminated in vacuo, the residue is taken up in ethyl acetate and washed successively with saturated aqueous sodium hydrogen carbonate solution and saturated aqueous sodium chloride solution. After drying with sodium sulphate the solvents are eliminated in vacuo and the residue is dried in vacuo.

1. temperaturerefluxed
2. temperaturethe mixture is refluxed for a further 2 hours
3. temperaturerefluxed for 16 hours
4. washwashed successively with saturated aqueous sodium hydrogen carbonate solution and saturated aqueous sodium chloride solution
5. dry with materialAfter drying with sodium sulphate the solvents
6. customthe residue is dried in vacuo