Hydrochloric Acid → 4-(4-(Trifluoromethoxy)phenyl)piperidine

HRID 102885Notes

Reaction equation

HRID 102885 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][cH:16][c:17]([O:20][C:21]([F:22])([F:23])[F:24])[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:26][OH:27].[CH3:28][OH:29].[ClH:25]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][cH:16][c:17]([O:20][C:21]([F:22])([F:23])[F:24])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887Methanol2×HCID 57666893Tert-butyl 4-[4-(trifluoromethoxy)phenyl]piperidine-1-carboxylate

Product 1

HCID 212682884-(4-(Trifluoromethoxy)phenyl)piperidine

Sources & evidence

ORD record
ord-a9bb176236474987b9bb7a6e866f7fe3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…