HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethynylthiophene → HCID 58168309, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethynylthiophene | HCID 3548422 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168309 | HCID 58168309 | 71.5% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 160 using Compound 83 (100 mg, 0.43 mmol) and 3-ethynyl-thiophene (70 mg, 0.65 mmol) to provide 167 (93 mg, 71% yield) as a white solid. LC-MS (M+H=303, obsd.=303).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-644f9271f0064f25b7d671b8cc791f11 |
| Source note | uspto-grants-2014_05 |