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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1029143Generated: November 2, 2026

HCID 58168295, compound → HCID 69815544, compound

https://huagongshe.com/reaction/1029143

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58168295HCID 58168295—
SolventHydrochloride methanolHCID 21893726—
ProductHCID 69815544HCID 69815544118.9%

Reaction Conditions

Temperature60 °C

Reaction Steps

Compound 178 (70 mg, 0.18 mmol) was dissolved in 1.5 M HCl/MeOH (5 mL), and stirred for 4 h at 60° C. The reaction solution was concentrated, and the resulting precipitate was dried under vacuum to provide 179 (60 mg, 92% yield) as a white solid. LC-MS (M+H=281, obsd.=281).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735584B2
Source datasetuspto-grants-2014_05
ORD IDord-2fcb9fd399304be9b000cde9afbf5e1a
Source noteuspto-grants-2014_05