HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-3-fluorophenol → HCID 58168352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-3-fluorophenol | HCID 2735919 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168352 | HCID 58168352 | 83.6% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 182 using Compound 83 (250 mg, 1.08 mmol) and 4-amino-3-fluoro-phenol (276 mg, 2.17 mmol) to provide 185 (290 mg, 83% yield) as a solid. LC-MS (M+H=322, obsd.=322).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-761df4ccabcc462c9312538aaeacb077 |
| Source note | uspto-grants-2014_05 |