HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-fluoroaniline → HCID 58168354, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-fluoroaniline | HCID 93898 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168354 | HCID 58168354 | 79.4% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 188 using Compound 83 (100 mg, 0.43 mmol) and 4-chloro-2-fluoroaniline (95 mg, 0.65 mmol) to provide 195 (116 mg, 79% yield) as a white solid. LC-MS (M+H=340, obsd.=340).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-8f14fd96d2ac49d0a1bbc3fab8cabb20 |
| Source note | uspto-grants-2014_05 |