HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2,5-dimethoxyaniline → HCID 58168058, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2,5-dimethoxyaniline | HCID 22833 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168058 | HCID 58168058 | 48.7% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 188 using Compound 83 (100 mg, 0.43 mmol) and 4-chloro-2,5-di-methoxyaniline (122 mg, 0.65 mmol) to provide 203 (80 mg, 48% yield) as a white solid. LC-MS (M+H=382, obsd.=382).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-96f590906932474e8175480b028b61b9 |
| Source note | uspto-grants-2014_05 |