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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1029192Generated: October 30, 2026

1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one → HCID 58168255, compound

https://huagongshe.com/reaction/1029192

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-oneHCID 58168008—
Reactant7-HydroxyquinolineHCID 135426866—
ProductHCID 58168255HCID 5816825569%

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 182 using 83 (50 mg, 0.22 mmol) and quinolin-7-ol (63 mg, 0.43 mmol) to provide 229 (51 mg, 69% yield) as a tan solid. LC-MS (M+H=340, obsd.=340).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735584B2
Source datasetuspto-grants-2014_05
ORD IDord-43be2edfbb6a4146a24fa437ea2ef301
Source noteuspto-grants-2014_05