HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethynyl-2-fluorobenzene → HCID 58168357, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethynyl-2-fluorobenzene | HCID 643358 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168357 | HCID 58168357 | 75% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 160 using 83 (100 mg, 0.43 mmol) and 1-ethynyl-2-fluorobenzene (0.07 mL, 0.65 mmol) to provide 259 (101 mg, 75% yield) as a tan solid. LC-MS (M+H=315 obsd.=315).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-0f69c78a58df4c889fb654088dd1ce9c |
| Source note | uspto-grants-2014_05 |