HRID1029239

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID20115387

未命名化合物

结构：CN(C)CCNC(=O)c1ccc2c(=O)[nH]c3nccc(Cl)c3c2c1

HCID69810673

未命名化合物

PRODUCTS

生成物

结构：CN(C)CCNC(=O)c1ccc2c(=O)[nH]c3nccc(Nc4ccc(NC(=O)c5ccc(F)c(F)c5)cc4)c3c2c1

HCID44206390

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized according to the procedure described for the preparation of Example 267 using 296 (40 mg, 0.12 mmol), and N-(4-amino-phenyl)-3,4-difluoro-benzamide (36 mg, 0.12 mmol) to provide 298. LC-MS (M+H=557, obsd.=557).

WORKUP

后处理

customThe title compound was synthesized

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9675bcbe0d2c4024a586bfdc026ddcaa
来源数据集: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08735584B2
来源说明: uspto-grants-2014_05

反应 SMILES

Cl[C:2]1[CH:11]=[CH:10][N:9]=[C:8]2[C:3]=1[C:4]1[CH:16]=[C:15]([C:17]([NH:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])=[O:18])[CH:14]=[CH:13][C:5]=1[C:6](=[O:12])[NH:7]2.[NH2:25][C:26]1[CH:31]=[CH:30][C:29]([NH:32][C:33](=[O:42])[C:34]2[CH:39]=[CH:38][C:37]([F:40])=[C:36]([F:41])[CH:35]=2)=[CH:28][CH:27]=1>>[F:41][C:36]1[CH:35]=[C:34]([CH:39]=[CH:38][C:37]=1[F:40])[C:33]([NH:32][C:29]1[CH:28]=[CH:27][C:26]([NH:25][C:2]2[CH:11]=[CH:10][N:9]=[C:8]3[C:3]=2[C:4]2[CH:16]=[C:15]([C:17]([NH:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])=[O:18])[CH:14]=[CH:13][C:5]=2[C:6](=[O:12])[NH:7]3)=[CH:31][CH:30]=1)=[O:42]