HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-iodopyridin-2-amine → HCID 58168188, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-iodopyridin-2-amine | HCID 22936596 | — |
| Reactant | [4-Fluoro-2-(methoxycarbonyl)phenyl]boronic acid | HCID 44717309 | — |
| Product | HCID 58168188 | HCID 58168188 | 21.3% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 1 using 4-chloro-3-iodopyridin-2-amine (1.20 g, 4.72 mmol) and 4-fluoro-2-methoxycarbonylphenylboronic acid (1.03 g, 5.19 mmol) to provide 411 (250 mg, 21% yield) as a solid. LC-MS (M+H=249, obsd.=249).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-4033339ca4df4d8ea4d17875c6c61ff1 |
| Source note | uspto-grants-2014_05 |