Triethylamine → HCID 86745617, compound

HRID 1029366Notes

Reaction equation

HRID 1029366 reaction equation
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.[Cl:25][C:26]1[CH:27]=[CH:28][C:29]2[S:33][C:32](SCC)=[N+:31]([CH2:37][CH3:38])[C:30]=2[CH:39]=1.C(N(CC)CC)C>CO>[Cl:25][C:26]1[CH:27]=[CH:28][C:29]2[S:33](=[C:6]3[C:5](=[O:7])[N:4]([C:8]4[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=4)[NH:3][CH:2]3[CH3:1])[CH2:32][N:31]([CH2:37][CH3:38])[C:30]=2[CH:39]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-HCID 13796806HCID 13796806, compound

Product 1

HCID 86745617HCID 86745617, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01) was mixed with 4.3 g (0.01 mol) 5-chloro-2-ethylthio-3-ethylbenzothiazolium tosylate in 15 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for 1 hour, then filtered and washed with methanol. After drying the yield was 2.20 g (59%), mp 161°-162.5° C., λmax=382 (ε=21,000).

Workup

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 2.20 g (59%), mp 161°-162.5° C., λmax=382 (ε=21,000)

Sources & evidence

ORD record
ord-6698c560f91c4bfbb5d68f41a2913471
Source dataset
uspto-grants-1992_04
Patent number
US05102781

Reaction notes

Loading…