Hydrochloric Acid → HCID 19900378, compound

HRID 1029392Notes

Reaction equation

HRID 1029392 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][C:5]([O:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16]([NH:18][C:19](=[O:29])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[N:26]([CH3:28])[CH3:27])=[O:17])=[CH:11][C:10]=2[CH3:30])=[N:6][CH:7]=1.[ClH:31]>C(OCC)C.C(Cl)Cl>[ClH:31].[Br:1][C:2]1[CH:7]=[N:6][C:5]([O:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16]([NH:18][C:19](=[O:29])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[N:26]([CH3:27])[CH3:28])=[O:17])=[CH:11][C:10]=2[CH3:30])=[N:4][CH:3]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 368697N-({4-[(5-Bromopyrimidin-2-yl)oxy]-3-methylphenyl}carbamoyl)-2-(dimethylamino)benzene-1-carboximidic acid

Product 1

HCID 19900378HCID 19900378, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

1.5 g of the desired product obtained in Example 1 (Compound No. 1 as described hereinafter) was dissolved in 20 ml of diethyl ether and 50 ml of methylene chloride, and hydrochloric acid gas was introduced to the solution and saturated therein.

Sources & evidence

ORD record
ord-1fe1e578dce04a718930d77356bdb6cc
Source dataset
uspto-grants-1992_04
Patent number
US05102884

Reaction notes

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