反应详情

A mixture of 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde (0.5 g) and hydroxylamine.hydrochloride (0.17 g) in ethanol (5 ml) was refluxed for 1.5 hours and evaporated in vacuo. The residue was triturated with ethyl acetate and recrystallized from a mixture of ethanol and ethyl acetate to give 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde oxime.hydrochloride (0.28 g).

1. temperaturewas refluxed for 1.5 hours
2. customevaporated in vacuo
3. customThe residue was triturated with ethyl acetate
4. customrecrystallized from a mixture of ethanol and ethyl acetate