Hydrogen Bromide → HCID 131717239, compound

HRID 1029407Notes

Reaction equation

[CH2:1]([CH:3]1[CH2:8][CH2:7][CH2:6][CH2:5][NH:4]1)[CH3:2].[BrH:9]>>[BrH:9].[CH2:1]([CH:3]1[CH2:8][CH2:7][CH2:6][CH2:5][NH:4]1)[CH3:2]

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 942052-Ethylpiperidine

Product 1

HCID 131717239HCID 131717239, compound

Procedure

(2S)-1-3-(2-phenylpyrazolo1,5-a]pyridin-3-yl)-acryloyl]-2-ethylpiperidine (trans isomer)(2.11 g) was converted to hydrobromic acid salt in a usual manner. The crystals were recrystallized from a mixture of ethyl acetate and acetone to give yellow crystals of (2S)-1-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)acryloyl]-2-ethylpiperidine.hydrobromide (trans isomer)(1.75 g).

Workup

customThe crystals were recrystallized from a mixture of ethyl acetate and acetone

Sources & evidence

ORD record: ord-18147fbc01574ad3af8a2296fdf76b64
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05102878

Reaction notes

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