反应详情

A mixture of 3-nitroso-2-phenylpyrazolo[1,5-a]pyridine (0.81 g) and zinc powder (0.95 g) in acetic acid (10 ml) was heated under reflux for 2.5 hours. The reaction mixture was poured onto ice-water (100 ml) and neutralized with saturated aqueous sodium bicarbonate solution. Resultant precipitates were collected by filtration, washed with water, and recrystallized from ethyl acetate to give crystals of 3-acetamido-2-phenylpyrazolo[1,5-a]pyridine (304 mg).

1. temperaturewas heated
2. temperatureunder reflux for 2.5 hours
3. additionThe reaction mixture was poured onto ice-water (100 ml)
4. customResultant precipitates
5. filtrationwere collected by filtration
6. washwashed with water
7. customrecrystallized from ethyl acetate