HCID 178439966, compound → HCID 178439984, compound

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Reaction Steps

6-Chloro-8-propyl-9-(2'-(tetrazol-5-yl)biphen-4-yl)methylpurine (0.030 g) was dissolved in ethanol (2 ml) and was stirred under an atmosphere of hydrogen in presence of Pd-C(10%) (0.01 g) for 24 hours. The catalyst was filtered off and the filtrate was evaporated to dryness giving the pure desired product as a glass like solid (0.020 g). NMR (CD3OD): δ1.0 (t, 3H, J=7.4 Hz), 1.8 (m, 2H), 2.88 (t, 2H, J=7.4 Hz), 5.56 (s, 2H), 7.1-7.34 (m, 5H), 7.45-7.7 (m, 4H), 8.90 (s, 1H), 8.98 (s, 1H). FAB-MS: m/e 397 (M+H). Analysis calculated for C22H20N8 : C, 66.00; H, 5.00; N, 28.00. Found: C, 65.57; H, 5.34; N, 27.67.

Provenance & Evidence