2,6-Dimethyl-8-ethyl-1-deazapurine → Hydrochloric Acid

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Reaction Steps

The title compound was prepared from 5,7-dimethyl-2-ethylimidazo[4,5-b]pyridine and N-triphenylmethyl-5-(4'-bromomethyl-4-chlorobiphen-2-yl)tetrazole in a manner similar to Example 7, and was isolated as an HCl salt. 1H NMR (300 MHz, CD3OD) δ1.38 (t, 3H), 2.72 (s, 6H), 3.28 (q, 2H), 5.82 (s, 2H), 7.18 (d, 2H), 7,36 (d, 2H), 7.44 (s, 1H), 7.58 (d, 1H), 7.72 (dd, 1H), 7.76 (d, 1H); FAB mass spectrum, m/e 444 (M+H, calcd for C24H22N7Cl, 444).

Provenance & Evidence