HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13543385, compound → HCID 15117289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13543385 | HCID 13543385 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 15117289 | HCID 15117289 | 92.3% |
Reaction Steps
A solution of ethyl (3S)-4-benzylmorpholine-3-carboxylate (6.50 g) in methanol (130 ml) was hydrogenated under atmospheric pressure of hydrogen over 20% palladium hydroxide on carbon (0.6 g) for 3 hours at ambient temperature. The catalyst was filtered off and the methanol was evaporated to give ethyl (3S)-morpholine-3-carboxylate (3.83 g) as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05102877 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-ecccfb36f93d4ad6b0c54ce3efb6372f |
| Source note | uspto-grants-1992_04 |