反应详情

A solution of 4-allyloxycarbonyl-2-[2-methyl-1,3-dioxolan-2-yl)morpholine (2.20 g) in acetone (22 ml) was stirred at ambient temperature for 5 days in the presence of p-toluenesulfonic acid monohydrate (1.10 g). The mixture was concentrated under reduced pressure to give a syrup. The syrup was subjected to a column chromatography on silica gel (25 g) and eluted with a mixture of hexane and ethyl acetate (9:1, V/V) to give 2-acetyl-4-allyloxycarbonylmorpholine (1.37 g) as a syrup.

1. concentrationThe mixture was concentrated under reduced pressure
2. customto give a syrup
3. washeluted with a mixture of hexane and ethyl acetate (9:1, V/V)