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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1029774Generated: October 26, 2026

Methyl (2R,3S)-3-(4-methoxyphenyl)-2-oxiranecarboxylate → HCID 15593400, compound

https://huagongshe.com/reaction/1029774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl (2R,3S)-3-(4-methoxyphenyl)-2-oxiranecarboxylateHCID 158607—
Reactant2-Amino-5-chlorobenzenethiolHCID 2737518—
ProductHCID 15593400HCID 15593400—

Reaction Steps

In the same way as in Example 1, the reaction between 2-amino-5-chlorothiophenol and methyl (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)propionate affords (+)-(2S,3S)-8-chloro-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-one. Melting point: 237°-241° C. [α]D20 =+91.9° (c=0.1; DMF).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05102998
Source datasetuspto-grants-1992_04
ORD IDord-6d36be52109d42b7a7971bf8a3fd1aee
Source noteuspto-grants-1992_04