2-Amino-4-methylthiazole → HCID 19901131, compound

HRID 1029801Notes

Reaction equation

HRID 1029801 reaction equation
[S:1]1[CH2:4][S:3][C:2]1=[C:5]([C:13](C(OOCC)=O)=[O:14])[C:6]([O:8][CH:9]([CH2:11][CH3:12])[CH3:10])=[O:7].[NH2:21][C:22]1[S:23][CH:24]=[C:25]([CH3:27])[N:26]=1>>[S:3]1[CH2:4][S:1][C:2]1=[C:5]([C:13](=[O:14])[NH:21][C:22]1[S:23][CH:24]=[C:25]([CH3:27])[N:26]=1)[C:6]([O:8][CH:9]([CH2:11][CH3:12])[CH3:10])=[O:7]

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 19901119HCID 19901119, compound

Product 1

HCID 19901131HCID 19901131, compound

Procedure

Following the procedure of Example 22, the titled compound was prepared as a white solid (67%) from sec-butyl 2-(1,3-dithietan-2-ylidene)-2-(ethoxycarboxycarbonyl)acetate and 2-amino-4-methylthiazole.

Sources & evidence

ORD record
ord-d8c3f86b46c04d01addd5383b6d9d2a4
Source dataset
uspto-grants-1992_04
Patent number
US05103013

Reaction notes

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