2-Amino-4-methylthiazole → HCID 19901138, compound

HRID 1029802Notes

Reaction equation

HRID 1029802 reaction equation
[S:1]1[CH2:5][CH2:4][S:3][C:2]1=[C:6]([C:13](C(OOCC)=O)=[O:14])[C:7]([O:9][CH:10]([CH3:12])[CH3:11])=[O:8].[NH2:21][C:22]1[S:23][CH:24]=[C:25]([CH3:27])[N:26]=1>>[S:3]1[CH2:4][CH2:5][S:1][C:2]1=[C:6]([C:13](=[O:14])[NH:21][C:22]1[S:23][CH:24]=[C:25]([CH3:27])[N:26]=1)[C:7]([O:9][CH:10]([CH3:11])[CH3:12])=[O:8]

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 19901126HCID 19901126, compound

Product 1

HCID 19901138HCID 19901138, compound

Procedure

Following the procedure of Example 22, the titled compound was prepared as a white solid (41%) from isopropyl 2-(1,3-dithiolan-2-ylidene)-2-(ethoxycarboxycarbonyl)acetate and 2-amino-4-methylthiazole.

Sources & evidence

ORD record
ord-21d64878f545448e8ec35081da21e61a
Source dataset
uspto-grants-1992_04
Patent number
US05103013

Reaction notes

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