Hydrochloric Acid → HCID 13121473, compound

HRID 1030087Notes

Reaction equation

HRID 1030087 reaction equation
[C:1]([CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[NH:13][C:14]3[C:15]([N:20]=2)=[N:16][CH:17]=[CH:18][CH:19]=3)=[C:8]([O:21][CH3:22])[CH:7]=1)([OH:3])=[O:2].Cl.[CH2:24](O)[CH3:25]>>[CH2:24]([O:2][C:1]([CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[NH:13][C:14]3[C:15]([N:20]=2)=[N:16][CH:17]=[CH:18][CH:19]=3)=[C:8]([O:21][CH3:22])[CH:7]=1)=[O:3])[CH3:25]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 13121472HCID 13121472, compound

Product 1

HCID 13121473HCID 13121473, compound

Procedure

1 g of 2-(4-carboxymethoxy-2-methoxyphenyl)imidazo(4,5-b) pyridine is dissolved in 20 ml of ethanol, the solution is saturated with HCl gas and allowed to stand overnight. After concentration and the usual work-up, 2-(4-ethoxycarbonylmethoxy-2-methoxyphenyl)imidazo(4,5-b)pyridine is obtained; hemifumarate, m.p. 198°.

Workup

  1. concentrationAfter concentration

Sources & evidence

ORD record
ord-63f9cc6e1fcb4aed8c198302b0f77669
Source dataset
uspto-grants-1992_04
Patent number
US05104881

Reaction notes

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