HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-chloro-4-(trifluoromethoxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Chloro-4-(trifluoromethoxy)benzoyl fluoride | HCID 19881753 | — |
| Product | 3-chloro-4-(trifluoromethoxy)benzamide | HCID 2773844 | — |
Reaction Steps
242.5 g (1 mol) of 3-chloro-4-trifluoromethoxybenzoyl fluoride were allowed to drop into 500 ml of 25% strength by weight aqueous ammonia solution with ice cooling, then the mixture was stirred for 30 minutes and the precipitate which deposited was filtered off with suction. 227 g of product having a melting point of 98° C. were obtained. This corresponds to a crude yield of 95% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05104879 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-0f6fb60eb044448a853f41f0561712a2 |
| Source note | uspto-grants-1992_04 |