Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4,7-Dichloroquinoline | HCID 6866 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 14837824 | HCID 14837824 | 70% |
Reaction Steps
A mixture of 1.98 g of 4,7-dichloro-quinoline, 1.38 g of 1,2,4-triazole and 10 ml of dimethyl formamide is stirred at 100° C. for 6 hours, whereupon the reaction mixture is poured into 100 ml of water and neutralized with 1 ml of a concentrated ammonium hydroxide solution. The precipitated product is filtered and recrystallized from ethanol. Thus 1.61 g of the desired product are obtained, yield 70%, Mp.: 169°-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05104884 |
|---|
| Source dataset | uspto-grants-1992_04 |
|---|
| ORD ID | ord-9354bc89c93740579913afba6a4e45da |
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| Source note | uspto-grants-1992_04 |
|---|
