HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-1,2,4-Triazole → HCID 14837825, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 4-Chloro-2,8-dimethylquinoline | HCID 809556 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 14837825 | HCID 14837825 | 88.1% |
Reaction Steps
A mixture of 1.91 g of 2,8-dimethyl-4-chloro-quinoline and 1.38 g of 1,2,4-triazole is melt at 120° C. and stirred for 2 hours. The solidified melt is dissolved in a mixture of ethanol and water. The solution is poured into a solution of 0.84 g of sodium bicarbonate and 20 ml of water. The precipitated product is filtered. Thus 1.97 g of the desired compound are obtained, yield 88%, m.p.: 99°-100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05104884 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-55034389cfa84a9f8639427fabb7ec3c |
| Source note | uspto-grants-1992_04 |